Diabetes, Heart and Cardiovascular Diseases News Chronicle.  Diabetes, Cardiovascular and Heart Diseases
 Article 311
    Published on March 6, 2018

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Instant protection from cardiovascular diseases with ischemic or cardiovascular preconditioning

Earlier studies show performing daily workout or exercise will stimulate heart and protect from heart diseases. Workouts also provide healthier heart over period of time. But it is less known that the heart of an individual will get marked clinical health benefits within hours even with a single bout of exercise or workout.


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Cardiovascular preconditioning is an experimental technique which was developed during mid-1980s to make the heart unsusceptible to future ischemia events. The concept behind this technique is to minimize ventricular arrhythmias and size of dead or dying tissue (infarct) by training the heart and coronary arteries with a brief period of ischemia condition. Restriction of blood supply causes a shortage of oxygen and glucose to heart tissues. The cardiovascular preconditioning event can be triggered by means of a short and non-fatal bout of exercise.

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A current study by researchers shows instant protection to the heart from cardiovascular diseases with ischemic or cardiovascular preconditioning by performing a single acute bout of exercise. Researchers have found heart health protection and prevention of heart tissue damage due to events such as myocardial infarction or heart attack with different types of exercises. Researchers say the heart can become more resistant to future ischemia events with frequent cardiovascular preconditioning events.

Researchers have conducted studies with animal models and the study results shows.


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  • A single workout session will provide long-lasting heart health benefits even after 24 hours.
  • A strong protection to heart health with one to three exercise or workout sessions per week.
  • Successive workout sessions will provide heart protection benefits by reactivating protective pathways associated with the first exercise or workout session.

Researchers say performing a regular acute bout of exercises will benefit even individuals with heart disease risk factors such as obesity and age. But those risk factors associated with heart diseases may prevent some immediate cardiac protective benefits.

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Protection to heart with exercise preconditioning is an inexpensive, easy and potent therapy. This effective and powerful therapy needs more awareness and optimal therapeutic usage.

Researchers say their findings may help in reducing mortality or death among those patients who are undergoing percutaneous coronary intervention treatment (PCI, also known as coronary angioplasty) with a cardiovascular preconditioning procedure. An optimum dosage of the workout or exercise should be designed for cardiovascular preconditioning procedure. They call for further studies among humans to confirm their findings.


Protection to the heart muscle from cardiovascular diseases by performing a single acute bout of an exercise workout.
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Lead author of the study was Professor Dick Thijssen, Ph.D., Department of Physiology, Radboud University, Nijmegen, The Netherlands. The study findings were published February 2018 in the journal JAMA Cardiology. Title of the article was "Association of Exercise Preconditioning With Immediate Cardioprotection." DOI : 10.1001/jamacardio.2017.4495


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