Diabetes, Heart and Cardiovascular Diseases News Chronicle. Diabetes, Cardiovascular and Heart Diseases. Article 288
Published on January 12, 2018 at 3:30 AM GMT


 



Too much sugar consumption causes liver, heart and cardiovascular diseases among healthy people

Too much sugar causes liver (NAFLD and NASH), heart and cardiovascular diseases among healthy people.

A study done by researchers at the University of Surrey, Guildford, United Kingdom, shows an increased risk of cardiovascular and liver diseases and increased fat levels in the bloodstream with the consumption of high quantities of sugar foods among healthy individuals.



Researchers have conducted studies with two groups of men. One group of men with high levels of liver fat (non-alcoholic fatty liver disease NAFLD) and another group with low levels of liver fat. They conducted experiments with a daily consumption of high or low sugar diet for 12 weeks duration. High sugar diet contains 650 calories worth of sugar and low sugar diet contains less than 140 calories worth of sugar.

Among high liver fat and healthy adult individuals and under daily consumption of high sugar diet, researchers have observed changes in the fat metabolism, which is a risk factor to cardiovascular diseases, stroke and heart attacks.

Among low liver fat and healthy adult individuals and under daily consumption of high sugar diet, researchers have observed changes in fat metabolism, increased liver fat and increased risk of NAFLD condition.



Most of the adults won't consume high levels of sugar. But teenagers and young children may consume high sugar levels by eating food rich in sugar, sweets and fizzy drinks. Researchers say these levels of sugar consumption by young people will increase risks to liver (NAFLD, NASH), heart and cardiovascular diseases as they grow up.

Co-author of the study was Bruce A. Griffin, BSc, PhD, RPHNutr, a biomedical scientist and also a Professor of Nutritional Metabolism, Faculty of Health and Medical Sciences, University of Surrey, Guildford, United Kingdom. The study findings were published October 17, 2017 in the Clinical Science. Title of the article was "Impact of liver fat on the differential partitioning of hepatic triacylglycerol into VLDL subclasses on high and low sugar diets."



       
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Fat metabolism : Our diet supplies fat requirements in the form of triglycerides. Fat will be converted into fatty acids and passes them into the bloodstream. The fatty acids will be consumed by our cells to produce energy and remaining fatty acids will be stored in fat cells (known as adipocytes) for future use. Fat metabolism is a biochemical process of breaking stored body fats and cells of our body uses these broken fat molecules to produce energy. Fats provide energy equals to 9 kcal/g compared to energy equal to 4.1 kcal/g with carbohydrates. Studies show our body uses more fat for fuel while walking. But our body burns more total calories while running and we lose more weight.

NAFLD : Liver produce energy from what we eat. This energy along with oxygen will be supplied to cells through our bloodstream. Normal liver contains some fat and weighs almost three pounds. It is called a non-alcoholic fatty liver disease (NAFLD) if there is a build-up of about 5 to 10 percent extra fat due to some reasons other than alcohol consumption. NAFLD is more common among women.

The severe form of NAFLD is called NASH (non-alcoholic steatohepatitis NASH). The liver may swell due to NAFLD and may lead to liver cancer or liver failure. About a quarter of citizens of the United States were affected with NAFLD. Risk factors for the development of NAFLD are

  • Diabetes or high blood sugar glucose levels
  • Overweight or obesity or high body mass index (BMI)
  • High triglycerides
  • High cholesterol
  • Quick weight loss
  • Poor eating habits

There are no known symptoms and medical treatment for NAFLD. But the diseases can be prevented or even reversed by reducing body weight, doing daily exercise or workout and by eating healthy diet.

NASH : See NAFLD.

 



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