Diabetes, Heart and Cardiovascular Diseases News Chronicle Diabetes, Cardiovascular and Heart Diseases. Article 281
Published on December 29, 2017 at 6:30 PM GMT

Quick diagnosis of heart damage, heart attack or acute myocardial infarction (AMI) with new blood biomarker

Diagnosis of heart damage attack with myosin-binding protein C cMyC biomarker at NHS United Kingdom. Current ECG tests and other test procedures can easily diagnose major heart attacks (or acute myocardial infarction AMI). But smaller or minor heart attack events are common and diagnosing them is challenging.

Current test procedures involves checking for biomarkers including cardiac troponin from the blood sample to detect heart damage or risk to heart attack in individuals reported with chest pain. The test classify an individual as low risk to heart attack if the cardiac troponin biomarker level is undetectable and the patient will be discharged from the hospital immediately. But up to 85 percent of the chest pain patients are being classified as an intermediate risk group, which requires overnight stay at hospital, further observation and blood tests and increased medical costs.

Now damage to heart can be detected quickly or instantly within 20 minutes with a new test biomarker developed by the scientists at King's College London, United Kingdom (UK). The new test procedure checks cardiac myosin-binding protein C (cMyC) biomarker in the blood. Researchers found that this biomarker in the blood is more sensitive in detecting heart muscle damage as its level increases rapidly to higher levels compared to troponin biomarker. Quick diagnosis of heart muscle damage can be done with this new test. Current test procedure is failing in proper detection of the heart muscle damage. But this test enables proper detection of heart attack. Patients without heart attack symptoms can be sent home quickly.

A study funded by the British Heart Foundation (a charity organization) has conducted tests to detect heart muscle damage with new test procedure among more than 2,000 people with acute chest pain in Europe. The new test found no heart attack incidents in double number of patients compared to existing troponin biomarker test. Researchers says the new test procedure will be implemented on the NHS within five years.

One of the lead researcher of the study was Dr Tom Kaier, BHF Clinical Research Fellow, King's College London. The study findings were published September 26, 2017 in the Circulation. Title of the article was "Direct Comparison of Cardiac Myosin-Binding Protein C With Cardiac Troponins for the Early Diagnosis of Acute Myocardial Infarction."

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Skipping breakfast can cause atherosclerotic plaques, cardiovascular and heart diseases
Skipping breakfast can cause atherosclerotic plaques, cardiovascular and heart diseases. A Spanish study results corroborate the significance of having breakfast for the health of the heart. This study shows double risk to the development of atherosclerotic plaques and cardiovascular diseases among those individuals who skip breakfast or if the energy value of their breakfast (in calories) is less than five percent of the recommended daily calories consumption compared to those individuals who ate high energy breakfast.

Researchers in their studies analyzed 4,000 middle aged individuals working in offices. Researchers monitored the events and the development of atherosclerotic plaques in them. Their routine breakfast calories consumption was as follows.

Researchers used ultrasound technology to find out atherosclerotic plaques in all the participants. When compared with participants who are under high-energy breakfast category, the study findings shows :

Lead author of the study was Irina Uzhova, a researcher from the Spanish National Center for Cardiovascular Research (CNIC), Department of Epidemiology, Atherothrombosis and Imaging (EAI), Madrid, Spain. The study findings were published October 2, 2017 in the Journal of American College of Cardiology (JACC). Title of the article was "The Importance of Breakfast in Atherosclerosis Disease: Insights From the PESA Study."

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