A study shows the duration of psoriasis increase the risk of inflammation in the blood vessels, cardiovascular diseases, heart attack and stroke
A study suggests there is an increased risk of heart attack and stroke in the people living longer with psoriasis. Psoriasis causes more systemic inflammation causing more damage to the vascular (a network of blood vessels) system. The people with psoriasis will be at a higher risk of heart diseases and stroke even if the people with psoriasis do not have other risk factors such as tobacco use, type 2 diabetes (high blood sugar levels) or old age.
Researchers have conducted imaging tests on 190 psoriasis patients. The study shows the intensity of the inflammation in the blood vessels is directly proportional to the duration of psoriasis in the patient. But imaging tests did not show an increased risk of heart attacks and stroke with the vascular (a network of blood vessels) inflammation.
To find out the association, a follow-up study on about 87,000 Danish adults (the average age is 54 years) with psoriasis and another 4.2 million adults without psoriasis shows 4,472 or 1.1 percent of adults with psoriasis disease had a major heart attack or stroke every year compared to 152,122 or 0.8 percent of adults without psoriasis disease. This study shows one percent increase in the risk of heart attack and stroke due to blood vessels inflammation in psoriasis patients.
Researchers hypothesized that chronic low-grade systemic inflammation (CLGSI) may be increasing the risk of cardiovascular diseases. The inflammation associated with psoriasis is similar to the inflammation process in the body which play a part in atherosclerosis (hardening of the arteries). But the researchers could not factor the influence of obesity and exercise as those data are not available.
The lead author of the study was Dr. Alexander Egeberg, Gentofte Hospital, Copenhagen, Denmark. The study was published August 18, 2017, in the Journal of the American Academy of Dermatology. Title of the article was "The relationship between duration of psoriasis, vascular inflammation, and cardiovascular events."
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Psoriasis : Psoriasis is a chronic, inflammatory and lifelong skin disorder due to the formation of scales and itchy, dry patches on the surface of the skin. This disorder may also affect the elbows, knees, scalp, joints, torso, palms, soles of the feet or nails. The disease affects both sexes, all ages and all races. This skin disorder may also cause pain and swelling in the joints. Psoriasis is associated with psoriatic arthritis. This disease worsens during cold winter months. But psoriasis is not a contagious disease.
Exact reasons for the risk of psoriasis is not known but the immune system, environmental factors and genetic predisposition may be the possible causes. Medical treatment to remove scales and to prevent a faster rate of development of skin cells may help but the disease can not be cured completely. This disease comes and goes and comeback. Measures such as no tobacco use, moisturizing skin and stress management may help.
The Diabetes News Chronicle does not provide medical advice, diagnosis or treatment. Information in Diabetes News Chronicle is to support and not to replace medical advice given by the surgeon or physician or doctor. Published article is not a medical advice by the OWNER of the "Diabetes News Chronicle" website or by the AUTHOR of the article.
Published by Jammi Vasista, Chennai, India.