Diabetes, Heart and Cardiovascular Diseases News Chronicle Diabetes, Cardiovascular and Heart Diseases. Article 265
Published on November 8, 2017 at 3:30 PM GMT

Higher risk to heart attacks, early death and all cause mortality with high levels of HDL or "GOOD" cholesterol

Higher risk to Heart Attacks, Early Death and All Cause Mortality with high HDL or GOOD Cholesterol levels. The NHS guidelines says HDL or "GOOD" cholesterol levels in an individual should be more than 1 mmol/liter, LDL cholesterol levels should be less than 3 mmol/liter and total cholesterol levels should be less than 5 mmol/liter. But there is no recommended maximum HDL cholesterol levels for an individual.

A current study findings shows double early death risk (or higher all-cause mortality risk) with high levels of HDL or "GOOD" cholesterol. The study results shows higher mortality rate of 106 percent among men and 68 percent among women with a high HDL cholesterol levels compared with those individuals who are with normal or moderate HDL cholesterol levels. Low HDL cholesterol levels in the blood stream too contribute to higher mortality. The study results shows individuals with moderate HDL cholesterol levels had lowest mortality.

Researchers came to above conclusion after conducting six years of follow up studies among 52,268 men and 64,240 women participants from Denmark. More than 10,500 deaths were registered among the participants during that period.

Researchers says their findings completely changes the current understanding on the HDL or "GOOD" cholesterol and effects on the heart health of an individual with high levels of HDL cholesterol. Researchers says HDL cholesterol level should be removed as an important health parameter and focus should be on the levels of triglyceride and LDL or "BAD" cholesterol levels. The following table defines high and moderate HDL cholesterol levels in the blood stream as per the researchers.

  High HDL Cholesterol levels Moderate HDL Cholesterol levels
Men 3.0 millimoles/liter 1.9 millimoles/liter
Women 3.5 millimoles/liter 2.4 millimoles/liter

Researchers adjusted their study findings with other risk factors such as body mass index (BMI), age, alcohol consumption, tobacco usage, physical activity and high blood sugar glucose levels (diabetes). But the study could not explain the cause-effect relationship between mortality risk and HDL cholesterol levels (either low or high).

Co-author of the study was Professor Borge G. Nordestgaard, Department of Clinical Biochemistry, Copenhagen University Hospital, Herlev, Denmark. The study findings were published on August 21, 2017 in the European Heart Journal. Title of the article was "Extreme high high-density lipoprotein cholesterol is paradoxically associated with high mortality in men and women: two prospective cohort studies."

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Heart specialist Dr Ross Walker says too much of exercise can lead to cardiac problems such as heart attack
Cardiologist Heart Specialist says too much of Exercise can increase Cardiac Heart Attack Problems. Sydney, Australia based preventative cardiology expert Dr Ross Walker says too much of exercise or workouts increases cardiac risks, especially among individuals of more than 40 years of age. He says an individual should do exercise between three to five hours per week for good heart or cardiac health. But doing exercise beyond five hours increases risks to heart attacks and heart diseases instead of giving additional health benefits.

Dr Ross Walker had found significant increase in the number of heart attack patients without heart disease risk factors such as high blood pressure or hypertension, obesity, overweight or high body mass index (BMI) or tobacco usage. Dr Ross Walker feels overstretching of the body organs including heart is a possible reason for the increase in the heart attacks in people without heart disease risk factors.

Dr Ross Walker advice regular heart check ups (or cardiac assessments) to those individuals who are aged over 40 years and want to continue high level of physical and sporting activities. He also says a competitive sport individual should focus on "moderate exercise" after reaching 30-35 years. They should undergo regular cardiac assessment or heart health checks if they want to continue playing competitive sport. Functioning of the heart will be affected by the health factors such as high blood pressure or hypertension, blood cholesterol levels, family history, body mass index (BMI), obesity and tobacco usage. The cardiac assessment test gives status of above risk factors.

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