Diabetes, Heart and Cardiovascular Diseases News Chronicle.  Diabetes, Cardiovascular and Heart Diseases
 Article 264
    Published on October 29, 2017

 

Wearable and disposable paper plaster device to measure sugar levels from the sweat to prevent hypoglycemia and seizure

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A previous study shows the risk of cardiovascular diseases and high blood sugar (glucose) levels can be reduced in patients with type 2 diabetes (T2D) with a regular workout (or exercise), a diet with low glycemic index foods and medications. The muscles and body cells consume more glucose (sugar) from the blood while doing exercise. The risk of hypoglycemia (low blood sugar levels) for a patient with diabetes during an exercise (or workouts) causes loss of consciousness or a seizure.



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A device to measure sugar levels from sweat during workouts (or exercise) for the prevention of hypoglycemia and seizure.

Researchers at the State University of New York, (Binghamton University or SUNY Binghamton) Binghamton have developed a biosensor patch to help a patient with diabetes from hypoglycemia while doing an exercise (or workouts). There are some flaws in the current devices using sweat to measure sugar levels in an individual. They are.

  • The existing devices fail to collect enough sweat sample for the analysis of glucose levels.
  • A risk of evaporation of the sweat in the existing devices.
  • The existing devices need a longer time to collect enough sweat sample for the analysis of sugar levels.

Researchers have eliminated the flaws in the new wearable and disposable paper plaster device. The device measures sugar (glucose) levels by collecting the sweat during the workout or immediately after the workout (or exercise). The procedure involved is a non-invasive procedure. This device does not require an external power supply. The investigator of this device was Seokheun Choi, Ph.D., an Assistant Professor, Electrical and Computer Engineering, the Binghamton University, Binghamton, United States.



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Seizure : It is a serious medical condition associated with extremely low sugar (hypoglycemia or insulin shock) or high glucose levels in the blood, especially in a patient with diabetes. This may not require emergency treatment. This may happen due to variations in the insulin levels, intercurrent disease (a disease during the course of another disease) or due to other metabolic factors.


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Cortical bone microstructure and tibia density deficits may increase fracture risk in elderly or senior people with type 2 diabetes

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Older (seniors) people with type 2 diabetes (T2D) are more likely to succumb to fractures compared to older people without type 2 diabetes (T2D) even though older people with type 2 diabetes (T2D) have normal to higher bone density compared with people without type 2 diabetes (T2D). Bone fractures may lead to decreased quality of life, disability and even death with increased medical costs.



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Bone fracture in patients with type 2 diabetes with cortical compact microstructure tibia density deficits.

A study shows bone density deficits in the distal tibia and cortical (or compact) bone microstructure is associated with an increased HbA1c (or blood sugar or glucose levels) in patients with type 2 diabetes (T2D). Researchers say that the traditional dual-energy X-ray absorptiometry (also known as DEXA, DXA, bone density scan or bone densitometry scan) cannot identify specific deficits in cortical (or compact) bone density in patients with diabetes.

Researchers conducted a study on 1000 women and men, with an average age of 65 years using a high-resolution peripheral quantitative computed tomography (HRpQCT) to compare the bone microarchitecture among healthy individuals and patients with type 2 diabetes (T2D). Results show a weakness in cortical bone microarchitecture (which cannot be identified in standard bone density testing equipment) among older patients with type 2 diabetes (T2D). Researchers say the fracture risk increases in patients with type 2 diabetes (T2D) due to the alterations in the microarchitecture of cortical (or compact) bone.


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Lead author of the study was Elizabeth J. Samelson, Ph.D., the Hebrew SeniorLife's Institute for Aging Research, Boston, United States. The study was published on September 20, 2017, in the Journal of Bone and Mineral Research. Title of the article was "Diabetes and Deficits in Cortical Bone Density, Microarchitecture, and Bone Size: Framingham HR-pQCT Study."



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Bone : There are two types of bone tissues. They differ in the microstructure. But they are biologically related.

  • Compact bone (or cortical bone) tissue, dense with the hard exterior.
  • Spongy bone (trabecular or cancellous bone) tissue, less dense with the hard exterior of the bone compared to the compact bone. This part of the bone contains red bone marrow, which produces blood cells.

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