Diabetes, Heart and Cardiovascular Diseases News Chronicle.  Diabetes, Cardiovascular and Heart Diseases
 Article 257
    Published on October 13, 2017

 

Abbott HeartMate 3 LVAD receives FDA approval for the treatment of heart failure

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The United States FDA has approved Abbott HeartMate 3 medical device. The Abbott HeartMate 3 is the only approved device for the ventricular assist device (VAD) to support as "bridge to transplant" therapy. This device simulates the beating of the heart (pulse) and helps the heart of the patient in pumping oxygen-rich blood to the body organs including the heart until the patient receives a heart transplant or a total artificial heart.



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Abbott HeartMate 3 LVAD receives FDA approval for the treatment of heart failure to support as a bridge to transplant.

The function of this device is safe and effective with fewer complications than the traditional left ventricular assist device (LVAD) (left-ventricular assist device). The clinical trial of HeartMate 3 medical device was published in February 2017. The result shows fewer problems with the device and the number of strokes to the patient compared with other models.

Life expectancy of a heart failure patient without the LVAD is 12 months or less. With the LVAD, 80 to 85 percent of heart failure patients are alive even after 12 months and 70 to 75 percent of heart failure patients survived even after 24 months. The longest survival with the LVAD was seven years.


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Medtronic also makes left-ventricular assist devices (LVADs) and is a competitor to the HeartMate 3 medical device. Cost of a LVAD is around $80,000 and the hospitals are willing to pay.



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LVAD : Left-ventricular assist device is an electromechanical device to help the heart failure patient in circulating oxygen-rich blood to body organs. The device can help partially or completely. They are different from the artificial hearts. Right ventricular assist device (RVAD) are the devices for the support of right ventricle of the heart. These devices are used as a bridge to transplantation and allow the body and the heart to rest, heal and help improve functionality.


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Abbott Laboratories : Abbott Laboratories is an Illinois, the United States based multinational healthcare company. Founded in 1888 by Calvin Abbott and the company deals with diagnostics, branded generic pharmaceuticals and medical devices. Abbott Laboratories products are being used worldwide by doctors, hospitals, laboratories and blood banks to diagnose and monitor the health of an individual.


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Too much salt consumption may double the risk of heart failure, stroke and coronary heart disease (CHD)

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The human body uses sodium to perform multiple biological functions such as flexing of the muscles, the function of the nerves and to maintain the fluid balance. The human body requires little salt (as salt contains sodium). The human body gets sodium from the food we eat. The World Health Organization (WHO) limits the salt consumption to five grams per day. Too much of salt consumption is bad for the health of an individual. The researchers are yet to find out the mechanism behind the increased health risks associated with the sodium consumption.



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Too much salt consumption may double heart failure, stroke and coronary heart disease (CHD).

A current study shows a twofold risk of heart failure with the increased consumption of salt. The study also shows a high salt consumption is associated with hypertension (high blood pressure) and the salt consumption is an independent risk factor for heart failure, stroke and coronary heart disease (CHD).

In the study, researchers used "24-hour sodium excretion" method to judge the salt consumption in 4,630 men and women participants, aged between 25 and 64 from the Finish data available at the National FINRISK Study and the North Karelia Salt Study. At baseline, researchers collected health habits, blood pressure (BP), height, body mass index (BMI), 24-hour urine samples and blood tests from the participants.


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Researchers equated one gram of sodium consumption to 17.1 millimoles (mmol) of excreted sodium from the collected 24 hour urine sample. Researchers followed the National Health Records of the participants for 12 years. They gathered new heart failure events and deaths related to heart failure from the Hospital Discharge Register, Causes-of-Death Register and the drug and treatment reimbursement records. They found 121 heart failure events.


The study shows that about two-times higher risk of heart failure in people consuming more than 13.7 grams of salt compared to people consuming less than 6.8 grams of salt. The risk of heart failure with the consumption of salt (or sodium) is independent of other risk factors associated with hypertension (or high blood pressure. BP). Researchers accounted for other risk factors for heart diseases in the study.


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The first author of the study was Professor Pekka Jousilahti, MD, Ph.D., Department of Chronic Disease Prevention, the National Institute for Health and Welfare, Helsinki, Finland. The study was presented to the European Society of Cardiology (ESC) Congress in Barcelona, Spain, on August 2017. Title of the article was "High salt intake associated with doubled risk of heart failure."



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