Diabetes, Heart, and Cardiovascular Diseases News Chronicle.  Diabetes, Cardiovascular, and Heart Diseases
 Article 247
    Published on September 16, 2017

 

Mothers With Preeclampsia During Pregnancy Are At A Higher Risk Of Heart Disease And Stroke

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A study at the Mayo Clinic, Minnesota, United States shows that a risk of atherosclerosis in women with a history of preeclampsia during pregnancy. The study has found that preeclampsia may follow a mother even in post-menopausal years.



A mother with preeclampsia during pregnancy is at a higher risk of heart disease and stroke later in the life.

The researchers have used the Rochester Epidemiology Project, which contains the health information of post-menopausal women who had either preeclampsia pregnancy histories or normal pregnancy histories. The study has found a higher risk of atherosclerosis in the post-menopausal years among those women who had preeclampsia history.


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The researchers have concluded that the complications from preeclampsia may extend beyond pregnancy. The American Heart Association acknowledges the risk of heart disease and stroke with preeclampsia. The authors say that the blood pressure and cardiovascular diseases should be monitored more closely in women who had preeclampsia.

The hidden risk such as preeclampsia or atherosclerosis will appear when a woman is carrying a baby (that is during pregnancy) as the blood volume increases by 30 to 50 percent and the heart will work harder in order to pump more blood as the pregnancy advances.

The study was published in September 2017 in the Mayo Clinic Proceedings. Title of the article was "Carotid Artery Intima-Media Thickness and Subclinical Atherosclerosis in Women With Remote Histories of Preeclampsia: Results From a Rochester Epidemiology Project-Based Study and Meta-analysis."
DOI: doi.org/10.1016/j.mayocp.2017.05.030



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A Risk Of Coronary Artery Disease And Heart Attack With An Elevated Calcium Level

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An earlier study shows that high levels of cholesterol, tobacco use, alcohol consumption, and diabetes are the main risk factors for heart diseases.


Risk of coronary artery disease (CAD) and heart attack (myocardial infarction. MI) with an elevated calcium level.

A study at the Karolinska Institutet, Stockholm, Sweden, shows the risk of heart diseases such as coronary artery disease (CAD) and heart attack (or myocardial infarction. MI) with elevated calcium levels in the bloodstream. The researchers say that a genetic predisposition is a possible reason for the increased levels of calcium in the bloodstream.



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The researchers have used the Mendelian randomization technique in a study on 184,305 individuals, to check the causal links between the calcium levels in the bloodstream and the risk of heart attack or coronary artery disease (CAD). Among them, 124,504 individuals were free from heart diseases and 60,801 individuals were diagnosed with coronary artery disease (CAD). Among the patients diagnosed with coronary artery disease (CAD), 70 percent of them had a heart attack. The researchers have accounted for six gene variants related to serum calcium levels.

The study shows that a higher risk of heart attack or coronary artery disease (CAD) with a higher level of calcium in the bloodstream. The higher serum calcium level in the bloodstream is due to the genetic predisposition. But the study could not find any strong evidence for the risk of coronary artery disease (CAD) or heart disease with calcium supplements in individuals who are genetically predisposed to the higher levels of calcium.


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The author of the study was Dr. Susanna C. Larsson. The study was published July 25, 2017, in the Journal of the American Medical Association (JAMA). Title of the article was "Association of Genetic Variants Related to Serum Calcium Levels With Coronary Artery Disease and Myocardial Infarction."
DOI: doi.org/10.1001/jama.2017.8981



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Calcium: Our body needs adequate supplies of calcium for the health of the bones and teeth, for the performance of the muscles, hormones, and nerves and for the blood to clot. About 99 percent of the calcium present in the body is being stored in the bones and teeth. Our body needs vitamin D to absorb and use calcium. Low levels of calcium (or hypocalcemia) may lead to osteoporosis.


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