Diabetes, Heart and Cardiovascular Diseases News Chronicle.  Diabetes, Cardiovascular and Heart Diseases
 Article 247
    Published on September 16, 2017

 

Mothers with preeclampsia during pregnancy are at a higher risk of heart disease and stroke

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A study at the Mayo Clinic, Minnesota, United States shows the risk of atherosclerosis in women with a history of preeclampsia during pregnancy. Researchers found that preeclampsia follows a mother even in post-menopausal years.



Mothers with preeclampsia during pregnancy are at a higher risk of heart disease and stroke later in life.

Researchers used the Rochester Epidemiology Project records. An analytical study of the health records of post-menopausal women who had either preeclampsia pregnancy histories or normal pregnancy histories. They found a higher risk of atherosclerosis in the post-menopausal years among those women who had preeclampsia history.


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Researchers concluded that complications from preeclampsia may extend beyond pregnancy. The American Heart Association acknowledges the risk of heart disease and stroke with preeclampsia. Authors say the blood pressure and cardiovascular diseases should be monitored more closely in women who had preeclampsia.

Hidden risks such as preeclampsia or atherosclerosis will appear when a woman is carrying a baby (that is during pregnancy) as the blood volume increases by 30 to 50 percent and heart work harder in order to pump more blood as the pregnancy advances.

The study was published in September 2017 in the Mayo Clinic Proceedings. Title of the article was "Carotid Artery Intima-Media Thickness and Subclinical Atherosclerosis in Women With Remote Histories of Preeclampsia: Results From a Rochester Epidemiology Project-Based Study and Meta-analysis."



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Risk of coronary artery disease (CAD) and heart attack (myocardial infarction. MI) with an elevated calcium levels

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Earlier studies show that high levels of cholesterol, tobacco usage, alcohol consumption and diabetes are the main risk factors for the heart diseases.


A risk of coronary artery disease (CAD) and heart attack (myocardial infarction. MI) with calcium.

A study at the Karolinska Institutet, Stockholm, Sweden, shows the risk of heart diseases such as coronary artery disease (CAD) and heart attack (or myocardial infarction. MI) with elevated calcium levels in the bloodstream. Researchers say a genetic predisposition is a possible reason for the increased levels of calcium in the bloodstream.



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Researchers used the Mendelian randomization technique in a study on 184,305 individuals, to check the causal links between the calcium levels in the bloodstream and the risk of heart attack and coronary artery disease (CAD). Among them, 124,504 individuals were free from heart diseases and 60,801 individuals were diagnosed with coronary artery disease (CAD). Among patients diagnosed with coronary artery disease (CAD), 70 percent of them have experienced the heart attack. Researchers accounted for six genetic variants related to serum calcium levels.

They concluded the study by stating that the higher risk of heart attack and coronary artery disease (CAD) with higher calcium levels in the bloodstream and a higher serum calcium levels in the bloodstream are due to genetic predisposition. But the researchers are unable to find any strong evidence for the risk of coronary artery disease (CAD) or heart disease with calcium supplements in individuals who are genetically predisposed to the higher levels of calcium.


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Author of the study was Dr. Susanna C. Larsson. The study was published July 25, 2017, in the Journal of the American Medical Association (JAMA). Title of the article was "Association of Genetic Variants Related to Serum Calcium Levels With Coronary Artery Disease and Myocardial Infarction."



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Calcium : Our body needs adequate supplies of calcium for the health of the bones and teeth, for the performance of the muscles, hormones and nerves and for the blood to clot. Bones and teeth store about 99 percent of our body calcium. Our body needs vitamin D to absorb and use calcium. Low levels of calcium or hypocalcemia may lead to osteoporosis.


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