A study at the Intermountain Healthcare, Salt Lake City, shows a double (or twice) risk of death in those patients of coronary artery disease who develop depression after coronary artery disease compared with patients with no depression. The study also shows a bidirectional relationship between heart disease and depression.
The study has found the risk of depression with the presence of heart disease and the worse outcome for heart disease in individuals with depression. The risk is independent of the time of diagnosis of depression.
A 10-year follow-up study on 24,138 patients of coronary artery disease has found that depression was a bigger and independent predictor of death. The study has evaluated other risk factors such as age, type 2 diabetes (blood sugar levels), heart failure, heart diseases, kidney failure, high blood pressure.
But, the study could not explain the reasons for the increased risk of death from depression. The researchers say that a patient of heart disease with depression may not take his regular medications, may not eat a healthy diet and may not be doing daily exercise.
The lead author of the study was Dr. Heidi May, Ph.D., a cardiovascular epidemiologist, Intermountain Medical Center Heart Institute, Salt Lake City, Utah, United States. The study was published on July 26, 2017, in the European Heart Journal - Quality of Care and Clinical Outcomes. Title of the article was "The association of depression at any time to the risk of death following the coronary artery disease diagnosis".
The World Health Organization (WHO) says that more than seven million individuals are dying in the world every year due to cardiovascular diseases and it is a leading cause of death. The coronary artery disease is a type of cardiovascular diseases (CVD).
A study at the University College London and the Imperial College London has analyzed the genetic data of 48,000 patients. The study shows a protective effect on coronary artery disease (CAD) with high levels of iron in the body. That means a higher risk for heart diseases with low levels of iron.
The researchers say that gender and age factors can affect the assessment of the risk of cardiovascular disease (CVD) with iron levels. The authors of the study say that the risk for further heart attacks can be lowered in patients of heart attack with low levels of iron by taking iron supplements.
The lead author of the study was Dr. Dipender Gill. The study was published on July 6, 2017, in the journal Arteriosclerosis, Thrombosis, and Vascular Biology. Title of the article was "The Effect of Iron Status on Risk of Coronary Artery Disease: A Mendelian Randomization Study-Brief Report."
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Published by Jammi Vasista, Chennai, India.