The Japanese researchers at Osaka University or Handai, Osaka, Japan made a significant step in preventing heart failure by inventing a sticking plaster harvested from the stem cells of an adult patient. Researchers found improvement in the heart function after one year with the sticking plaster developed from the stem cells retrieved from the thigh and transplanting it onto the heart. Authors of the study say their therapy can become a long-term solution for the problems associated with heart disease. They also say their study requires clinical follow up with a larger study to confirm their discovery. Professor Metin Avkiran from the British Heart Foundation hailed this breakthrough. The study findings were published in the journal of the American Heart Association.
A study by researchers at the University of Pennsylvania, Philadelphia, United States shows nine percent lower chance of dying (or more survival advantage) by transplantation of diabetic donor kidneys instead of remaining on the waitlist. Diabetic donor kidneys can shorten waitlist times. Benefits will be more in patients with high mortality risk with long wait times. This study shows usage of deceased donor kidneys by a patient who requires kidney instead of rejecting them as the demand for kidney donor organs continues to outpace the supply.
In the current study, researchers used the Organ Procurement and Transplantation Network (OPTN) database operated under contract with the United States Department of Health and Human Services. Researchers compared 8,101 individuals who undergone diabetic donor kidney transplantation with 126,560 individuals who undergone non-diabetic donor kidney transplantation. Researchers have done 8.9 years of follow up studies. The study shows mortality rate was 35 deaths per 1000 person-years and nine percent lower odds of dying from any cause in those individuals undergone diabetic kidney transplantation when compared with those individuals who are in waitlist or finally received a non-diabetic donor kidney. Author of the study was Jordana B Cohen, MD, MSCE, from the University of Pennsylvania, Philadelphia, United States and the study findings were published in the Journal of the American Society of Nephrology.
A study by researchers at the Queen Mary University of London shows statins medications can reduce stress on the heart and risk of heart diseases apart from reducing "BAD" or LDL cholesterol levels in the blood. The thickness of the heart is a good predictor of the future risk of heart attacks and statins can reduce the thickness of the heart. They are very effective in lowering blood pressure and improving blood flow apart from reducing stress on the heart.
To find out the link between heart and statins, researchers conducted studies among 4,500 individuals without heart diseases and assessed volume and mass of the heart with the help of MRI scans. The study found lower volumes in left and right ventricular and lower mass in left ventricular. This shows patients using statins unlikely to have large heart chamber. Statin drugs reduce inflammation, improves blood vessels function and stabilize plaques formed in the blood vessels. Negative changes in the heart can also be reversed with statin drugs.
But the health experts say statins should not be prescribed automatically to every individual aged over 40 years. The lead scientist of the study was Dr. Nay Aung, the Queen Mary University of London and the study findings were presented in the annual meeting of the European Society of Cardiology (EuroCMR 2017) held in Prague, Czech Republic.
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Published by Jammi Vasista, Chennai, India.