Diabetes, Heart and Cardiovascular Diseases News Chronicle.  Diabetes, Cardiovascular and Heart Diseases
 Article 8
    Published on June 8, 2016

 

The Trial Of Oral Insulin

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A trial of oral insulin on patients of diabetes in midstage by Oramed Pharmaceuticals Inc, Israeli shows.

  • A Lower nighttime blood glucose levels.
  • No side effects such as dangerously low blood sugar levels.
  • About 90 percent of the patients are of type 2 diabetes (T2D).

The insulin pill will have a protective coating and a high dose of insulin. The insulin in the pill is much closer to the natural insulin. The tested oral insulin goes from the gut to liver but an injected insulin goes from blood to liver.


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A high levels of insulin circulating in the body increases the health risks. The new drug will be known as ORMD-0801.



       
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About Loss Of Islet Sympathetic Nerves

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A study on the islet cells in the pancreas in the patients with type 1 diabetes has found marked and sustained loss of islet sympathetic nerves. But there was no loss of islet cells in the patients with type 2 diabetes (T2D).

The author of the study was Thomas O. Mundinger, from the University of Washington, Seattle, the United States. The study was published online in the Diabetes.


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About Diabetic Ketoacidosis

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Diabetic ketoacidosis is a serious complication of diabetes. This disease occurs when the body produce a high level of acids in the blood called the ketones.

The human body can not produce enough insulin during the diabetic ketoacidosis. The Insulin helps us in passing the energy from the blood to the cell.


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About Insulin Pump Therapy

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According to the Diabetes Technology and Therapeutics (DTT) published in the Liebertpub, insulin pump therapy is a developing technology. A patient of either type 1 diabetes or type 2 diabetes can control the blood sugar (glucose) levels in a better way.

Now, the pumps are much smaller and can be operated remotely by a Smartphone.


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About Ascensia Diabetes Care

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There are wireless devices in the market to measure blood glucose levels via Bluetooth connectivity. These devices are made by the Ascensia Diabetes Care under the trademark CONTOUR NEXT ONE and CONTOUR PLUS ONE. The patient can get a feedback on blood glucose levels and can the device can send a reminder or alert message. These devices have the CE Mark.


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Discovery Of T Cells

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The researchers from the Cardiff University Institute of Infection and Immunity has found that the germs can destroy the insulin secreting islet cells leading to type 1 diabetes.

An earlier study has found that the T-cells, a type of white blood cell in the body, is extremely effective in protecting from the germs. But the same T-cells will be activated by the bacteria to play a major role in destroying the insulin producing beta cells.


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The germs may trigger the immune system of the body to destroy the cells that secrete insulin. The behavior of the T-cells is like a friendly fighting or a mistaken identity. The T-cells unnecessarily fight with the beta cells.

The scientists are hoping that a further research may show a treatment for the prevention of type 1 diabetes (T1D). Even the children are suffering from type 1 diabetes (T1D). Type 1 diabetes is not connected with diet. The research was published in the Journal of Clinical Investigation.


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Warning Signs Of Type 1 Diabetes

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About 5 percent of the children with type 1 diabetes (T1D) die in the sleep. This is known as "Dead In Bed Syndrome". Warning signs of type 1 diabetes in the children are.

  • Urinating often.
  • A desire to drink more water.
  • Eat more food.
  • An extreme weakness and tiredness.
  • Weight loss without reason.
  • Vision problem.


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