Diabetes, Heart and Cardiovascular Diseases News Chronicle.  Diabetes, Cardiovascular and Heart Diseases
 Article 59
    Published on September 17, 2016

Hypocalcemia & Hypomagnesemia Risks To Babies Of Mothers With Diabetes

A research by Italian researchers shows a newborn child of the mother with diabetes, before becoming pregnant or with gestational diabetes during pregnancy, are at 10 to 36 times increased risk of neonatal hypoglycemia. Other increased risks are jaundice, hypocalcemia and hypomagnesemia, growth in the child, malformations and cesarean rate. Researchers found that a higher risk of respiratory distress and polyhydramnios in newborn babies are due to pre-gestational diabetes. Researchers say greater care should be taken if the pregnant woman is with diabetes or with gestational diabetes (GD). Baby delivery will be complicated if the pregnant women are with other complications such as hypertensive and thyroid disorders. Researchers found a number of abnormalities in children born to women with diabetes prior to pregnancy or with gestational diabetes (GD) during pregnancy. Lead author of the study is Dr. Basilio Pintuadi, MD, Niguarda Ca' Granda Hospital in Milan, Italy and research findings were presented during the annual meeting of the EASD (the European Association for the Study of Diabetes).

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Hypocalcemia : Hypocalcaemia or hypocalcemia is the condition where blood contains less than 8.8 mg/dL of serum calcium. Osteoporosis is a disease in the body due to long-term deficiency of calcium. Bones become brittle and may fracture due to small impact. Babies with calcium deficiency are jittery and show tremors but mostly show no symptoms. Common reasons for hypocalcemia are vitamin D deficiency and chronic kidney disease. Calcium is regulated by the parathyroid hormone (PTH).

Osteoporosis : Refer hypocalcemia.

Hypomagnesemia : Hypomagnesemia (or hypomagnesaemia) is an indication of magnesium deficiency in the blood, value less than 1.7 mg/dL. Magnesium deficiency leads to tiredness, lethargy, anorexia, nausea, vomiting, weakness, personality change, tetany tremor, cramps and high or low heartbeats. Hypomagnesemia condition may lead to hypocalcemia too. Green vegetables are a rich source of magnesium.

Thyroid : Thyroid is a gland in the front of the neck making important thyroid hormones, T3 and T4, affecting the metabolism of the body. Body is under hyperthyroidism when the thyroid gland produces excess hormones. The most common disease due to hyperthyroidism is Graves' disease (also known as toxic diffuse goiter) which is an autoimmune disease affecting thyroid gland resulting enlargement of the gland. Insufficient production of thyroid hormone is hypothyroidism which is caused due to iodine deficiency.


Merger Between Glooko and Diasend

Glooko and Diasend are merging together to become a unified company. They are going to operate with the trade name Glooko. The joint platform is going to download data from 160 types of devices worldwide such as glucose meters, insulin pumps, continuous glucose monitors and activity trackers. They are planning to merge their products and deliver a single product line to the market during the next one year.

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Glooko : Mountain View, California based Glooko, Inc was established in 2011. The company offers a unified diabetes platform to bring diabetes patients data such as diet, blood glucose levels, fitness, insulin, biometrics, medication data from multiple devices through its Glooko mobile app. The app can be downloaded from Google Play and Apple App store supporting both iOS and Android.


Discovery Of Fast Acting Insulin Of Conus Geographus

Researchers from Australia and the United States discovered that a Con-Ins G1 protein found in the venom of Conus geographus operates faster than human insulin. Conus geographus (also called geography cone or the geographer cone) predatory cone snail, living in reefs of tropical Indian Pacific oceans. They hunt small fish. Researchers say insulin-containing venom puts the small fish into a state of hypoglycemia (low-glucose) shock. The discovered protein can be used for the treatment of diabetes. Prof Mike Lawrence at Walter and Eliza Hall Institute (WEHI), Melbourne, Australia and his colleagues participated in this study. Study results were published in the journal Nature Structural & Molecular Biology.

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