Diabetes, Heart and Cardiovascular Diseases News Chronicle Diabetes, Cardiovascular and Heart Diseases. Article 55
Published on September 13, 2016 at 05:30 PM


Hypoglycemia & HbA1c. Approval Of Diabetes Drug Xultophy Liraglutide From Novo Nordisk

Type ii diabetes (T2D) drug Xultophy (insulin/liraglutide) manufactured by Danish firm Novo Nordisk is an insulin-based combination therapy drug. The European Commission approved it during 2014. Now the company got approval for expanded usage as drug trials (LIRA-RENAL trials) with oral glucose lowering medicines shows improved glycaemic control. Side affects such as weight gain and hypoglycemia too reduced. There is marked reduction of HbA1c and low rate of hypoglycemia.


       
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Also related to this story
1. Risks To Severe Hypoglycemia
2. Study To Reduce Nocturnal Hypoglycemia
3. Study On HbA1c Levels
4. About HbA1c Test
5. Trials With Forxiga (Dapagliflozin), Victoza (Liraglutide) And Insulin Approach (Triple Therapy)

Hypoglycemia : Low blood sugar levels in the body is known as hypoglycemia. Blood sugar levels keep on changing throughout the day. Common reasons for hypoglycemia are

Symptoms for low blood sugar levels or hypoglycemia in an individual are

HbA1c : HbA1c stands for glycated hemoglobin. Hemoglobin is a protein in the red blood cells and they supply oxygen to all cells in the body. Along with oxygen, they collect glucose and becomes glycated. We get average blood sugar levels over a period of three months by measuring glycated hemoglobin (HbA1c) as the life span of a red blood cell is four months. As the HbA1c value increases, risk to diabetes (and diabetes related diseases) increases. This test is a reliable indicator for the blood glucose levels and diabetes.

 

Hyperglycemia & New AP39 Drug To Prevent Blood Vessel Complications Due To Hydrogen Sulfide (H2S)

All living cells in our body makes and responds to tiny amounts of hydrogen sulfide (H 2 S). When living cells were stressed due to disease, they makes tiny quantities of hydrogen sulfide (H 2 S) from the enzymes to keep mitochondria generating energy and cells to function. High blood sugar or glucose levels (called hyperglycemia) damages endothelial cells that contains mitochondria and make mitochondria inefficient and leaky. A study done on mouse models shows newly developed AP39 diabetes drugs can be used to target hydrogen sulfide gas present in our blood vessel cells to restore efficiency of the mitochondria and prevent blood vessels complications (in heart, eye and kidneys) in diabetes patients. Research team was led by Matthew Whiteman from the University of Exeter Medical School, Exeter, England and study results were published in the journal Pharmacological Research.


       
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Also related to this story
1. Device To Release Drugs In Eye
2. Device To Predict Diabetes
3. Risks With Cortisol (Stress Hormone) And Apnea Or Apnoea
4. Total Daily Energy Expenditure, METs And Hot Bath
5. Dyslipidemia And Risks To Cardiovascular Disease (CVD) And Ischemic Heart Disease (IHD)

Mitochondria : Mitochondria is a specialized and organized structure in our body's living cells and each cell contains mitochondria varying from a single unit to thousands. Mitochondria performs biochemical process of aerobic cellular respiration (glucose is oxidized and release energy. Nutrients converted into adenosine triphosphate, ATP) and release waste products such as carbon dioxide CO 2 .

Hyperglycemia : Excess sugar or glucose levels in the blood, an important indicator for diabetes and is called as hyperglycemia. Main reasons for hyperglycemia is consumption of excess carbohydrates than normal and leading sedentary life. Hyperglycemia can lead to severe health complications such as nerve damages, kidney diseases etc. Main symptoms for hyperglycemia are

 

Rickets Osteomalacia Diseases Prevention With Vitamin D
A study involving over 76,000 people shows that risk to type 2 diabetes (T2D) will be cut by 62 percent in those individuals having highest amounts of Vitamin D. Researchers says Vitamin D reduces insulin sensitivity and reduce blood sugar levels.

       
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1. Nephropathy Risk With Vitamin D Deficiency
2. Treatment With Vitamin D Taken With Quetiapine
3. Device To Detect Deadly Ketones
4. About Revita DMR Device
5. Risks To Left Ventricle And Heart Health

Vitamin D : Vitamin D is essential for the body for the absorption of minerals from the food such as calcium, phosphate, magnesium, iron and zinc. Vitamin D prevents softening and weakening of bones (rickets disease) in children and soft or fragile bones (called osteomalacia disease) in adults. This vitamin is available in few foods and added in other foods as dietary supplements. Our skin can make vitamin D from sun's ultraviolet rays. Our body can store excess vitamin D quickly in fatty fat and release it when required.

 

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Diabetes News Chronicle does not provide medical advice, diagnosis or treatment. Information in Diabetes News Chronicle is to support and not to replace medical advice given by surgeon or physician or doctor. Published article is not a medical advice by the OWNER of "Diabetes News Chronicle" website or by the AUTHOR of the article.


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