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Article 35 Published on August 1, 2016
PolyNovo Limited (formerly Calzada limited), Melbourne Australia based company partnered with Prof Toby Coates and Prof John Greenwood to find alternative technology to islet cell transplantation for the treatment individuals with type 1 diabetes (T1D).
Benefits With Brisk Walk
A study by Duke University School of Medicine shows Brisk walk is more effective compared with jogging in reducing blood glucose levels in prediabetes individuals. They say high-intensity exercise burns more glucose and moderate intensity exercise burns more fat. A brisk walk of 11.5 miles per week is better than 11.5 miles of jogging for prediabetes individuals. Lead author of the study is Dr. William Kraus, M.D. The study was published in the journal Diabetologia.
About Beta Cell 'Hubs'
A study by Dr. David Hodson, University of Birmingham says 65% to 80% of islet cells are of beta cells. The study found that just one to ten percent of beta cells control islet response to blood glucose. Failure of this few cells leads to diabetes. The study was conducted on mice, rat and human models. The study was published in Cell Metabolism.
Benefits With breastfeeding
A study by researchers from Helmholtz Zentrum Muenchen Germany says women with gestational diabetes (GD) after pregnancy can protect themselves against the development of type 2 diabetes (T2D) by breastfeeding for more than three months. The three months of breastfeeding will bring long-term metabolic changes and gets protection from type 2 diabetes (T2D) for at least 15 years.
Diabetes Gender Specific Factors
Gender is not considered a factor in the international guidelines for the management of type 2 diabetes (T2D). A study by Alexandra Kautzky-Willer, Medical University of Vienna, Austria says diabetes treatment should be gender specific as the risk factors and their effects on type 2 diabetes (T2D) individuals are different with respect to men and women. Researchers say gender-specific factors should be incorporated in the international guidelines for the management of diabetes mellitus. The differences are
- Women are protected from type 2 diabetes (T2D) due to the production of estrogen hormone (until menopause), unlike men
- Women are protected from type ii diabetes (T2D) due to thigh fat due to genetics and estrogen, unlike men
- Stomach circumference in women has a better diabetes predictive power than in men
- Women are at an enhanced risk of type 2 diabetes (T2D) due to psychosocial and job stress unlike men
- Lack of sleep is more frequent in women, increases the risk of type 2 diabetes (T2D)
- Men are at a risk of diabetes due to stomach fat, liver fat and lower sensitivity to insulin, unlike women
- Manufactured substances bisphenol A or phthalate are risk factors to diabetes but effects are different in men and women
- Researchers found women specific biomarkers, protein Fetuin-A (formed by the liver) and Copeptin (also known as CT-proAVP) can help in detecting the risk of diabetes early in women
- Levels of proneurotensin, a diabetes biomarker is higher in women than in men.
Risk With Teenage Obesity
A study by researchers from Sheba Medical Center, Israel found that obesity during teenage causes death. They are at a five-fold death risk due to coronary heart disease, a three-fold death risk due to cardiovascular causes and a two-fold death risk due to stroke during later in life. The study was published in the New England Journal of Medicine on Apr 13, 2016.
Approval Of Synjardy Drug
FDA approved the Synjardy drug that improves glycemic control in adults with type 2 diabetes (T2D). Synjardy is a single pill combination drug containing empagliflozin and metformin hydrochloride. The drug reduced A1C levels significantly after 24 weeks. The most common side effects of the drug are nausea, vomit and tiredness.
About Qtern Drug
Qtern with metformin combination shows a significant reduction in HbA1c when compared with other combination drugs. The European Commission gave nod for the drug in all 28 member countries and Iceland.
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