While studying mice, researchers from universities of Edinburgh and Ljubljana found a gene that protects them from a high-fat diet. The found gene codes to a protein called TST. high-fat cells build up waste products during a high-fat diet. TST protein will detoxify harmful waste build up in the fat cells. Researchers gave a drug that activates TST in a mice model which is obese and suffering from diabetes disease. They found that mice lost weight and severity of diabetes was reduced. Researchers say details of the genes of healthy leanness could lead us to a new approach in treating diabetes associated with obesity. TST levels can be boosted with thiosulfate drug which is used as an antidote for cyanide poisoning and first used 80 years ago. The study was published in journal Nature Medicine.
The research conducted by Dr. Joshua J Joseph (Johns Hopkins University, Baltimore) examined links between incidents of type 2 diabetes (T2D) and cardiovascular health on multi-ethnic population in the US between 2002 and 2012. The study shows that 60% of the diabetes cases attributed to poor cardiovascular health factors. Cardiovascular disease (CVD) and diabetes have common risk factors. They are
Cardiovascular health can be improved by
Mortality rate with CVD is three times higher for patient with diabetes compared with a patient without diabetes. The study was published in the Diabetologia.
This study involves examination of DNA samples of patients with diabetes to identify genetic factors in developing kidney disease. Diabetes is a leading cause of kidney failure and is often detected at an advanced stage. A five-year old study was started at Queens University, Belfast and got grants under US-Ireland Research and Development Partnership Program. The study was conducted by
Professor Peter Maxwell says the project has three main goals. They are
Rozalina McCoy, MD, an endocrinologist at the Mayo Clinic in Rochester have gone through records of 31,542 adults and found a double risk of severe hypoglycemia in a patient taking more glucose-lowering medications than recommended. The study was published in the JAMA Internal Medicine.
A study conducted by Christopher Fagundes and Kyle Murdock of Rice University found a link between emotional stress and diabetes. Brain defaults make some people not able to handle emotional stresses and may lead to anxiety. Diabetes and high blood glucose levels may be activated due to anxiety through the metabolic pathway. The study was published in the Psychoneuroendocrinology.
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Published by Jammi Vasista, Chennai, India.