Diabetes, Heart and Cardiovascular Diseases News Chronicle. Diabetes, Cardiovascular and Heart Diseases. Article 149
Published on March 5, 2017 at 04:00 PM GMT


 



Desire To Sleep Early Is A Warning Sign Of Heart Disease

Researchers analyzed hospital admission records of heart attack patients and their deaths in England between 2006 and 2010. Researchers found that 16 percent of the patients those died due to a heart attack within 28 days of admission had not been diagnosed. A study done by researchers from Imperial College, London shows men desiring to sleep early could be an important warning sign of heart disease in men. Sleeping more time may not relieve people from this condition.

The researchers looked into sleeping habits of 2,400 men and found that individuals with very high levels of blood pressure (hypertension) want to sleep early compared with healthy people. The individuals with a heart condition could experience terrible sleep throughout the night with sleep score of 5.3 (poor sleep). Researchers say the desire to sleep early is associated with hypertension. The leader of the study is Dr. Nobuo Sasaki from Hiroshima University and the study findings were presented at the European Society of Cardiology held in Rome.



       
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Better Health Outcomes With Newer Type 2 Diabetes Drugs

A large clinical trial done by researchers from Karolinska Institute in Stockholm shows newer oral drugs to treat type ii diabetes (T2D) compared with insulin resulted in better blood sugar or glucose levels control and less number of heart events after a year.

A clinical trial compared insulin treatment with two classes of oral glucose-lowering drugs (GLDs), sodium glucose cotransporter-2 (SGLT2) and dipeptidyle-peptidase-4 (DPP-4) inhibitors among 20,000 Swedish individuals with type 2 diabetes over 1 year period. Researchers measured effects of these drugs against insulin on cardiovascular diseases (CVD), severe hypoglycemia and all-cause mortality. Apart from above studies, researchers studied health outcome between DPP-4 inhibitors and dapagliflozin (SGLT2 drug) used in the study.

The clinical findings show

  • Lower risk of all-cause mortality by 44 percent with oral glucose-lowering drugs (GLDs) group compared with insulin group
  • Reduction to cardiovascular diseases (CVD) incidents by 15 percent in oral glucose-lowering drugs (GLDs) group compared with insulin group
  • Reduction to hypoglycemia incidents by 74 percent in oral glucose-lowering drugs (GLDs) group compared with insulin group

Clinical studies on health outcomes between dapagliflozin (Forxiga) and DPP-4 inhibitors show

  • Reduction in risk of all-cause mortality by 56 percent with dapagliflozin (Forxiga) drug compared with DPP-4 inhibitors
  • Reduction in risk of cardiovascular disease events by 49 percent with dapagliflozin (Forxiga) drug compared with DPP-4 inhibitors

The above clinical findings show oral glucose-lowering drugs (GLDs) are better compared with insulin for reducing risks with hypoglycemia, cardiovascular diseases (CVD) and all-cause mortality.



       
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Possible Cause To Type 2 Diabetes And Heart Disease is Abdominal Fat

A study done by researchers shows the possible factor behind the development of coronary heart disease and type 2 diabetes is abdominal fat. Individuals with higher waist to hip ratio, adjusted for body mass index (BMI) are likely to be at increased risk of the development of health risks.

Researchers conducted studies to find the association between the increased waist-to-hip ratio (WHR) adjusted for BMI and the development of type 2 diabetes (T2D), coronary heart disease and cardiometabolic traits. Glucose or sugar, lipids, insulin levels in the blood and systolic blood pressure are cardiometabolic traits. Author of the study is Dr. Sekar Kathiresan, Massachusetts General Hospital in Boston and the study findings were published in the JAMA.



       
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Also related to this story
1. Improved Mortality Among Older Type 2 Diabetes Individuals With Metformin
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