Diabetes, Heart and Cardiovascular Diseases News Chronicle. Diabetes, Cardiovascular and Heart Diseases. Article 140
Published on February 22, 2017 at 11:30 AM


 



Drug To Treat Infection Behind Cardiovascular Disease

Lycotec drugs to treat bacterial infection causing cardiovascular disease CVD plaque atherosclerosis.

A Nutra-Pharmaceuticals class drug developed by UK based Lycotec Ltd for the treatment of a bacterial infection has filed a patent application. The new drug molecules are of food origin present in the Mediterranean diet and safe to consume. This is a first drug for the treatment of a bacterial infection that causes the development of cardiovascular disease (CVD) and atherosclerosis in an individual. In atherosclerotic plaques of people with cardiovascular disease (CVD), researchers identified a number of viruses and bacteria during the last three decades. Infections due to these bacteria and viruses are the reasons for the bad condition of atherosclerosis and CVD.

In multiple clinical studies, administration of this oral drug for 4 weeks duration has reduced anti-chlamydia antibodies and blood markers of oxidative-inflammatory damage in 85 percent of the patients with cardiovascular disease with double-blind and placebo-controlled individuals. The manufacturer is going to present the drug and clinical trial results at CBRS Conference in Charlotte, NC, in April 2017. Lycotec company is currently looking for a funding deal with other pharma company. One of the inventors of this drug is Dr. Ivan Petyaev, founder of Lycotec. Co-author of this invention is Prof Nailya Zigangirova.



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About Qtern Combination Drug From AstraZeneca

DPP-4 Saxagliptin & SGLT2 Dapagliflozin Qtern drug to control (glycemic) blood sugar glucose levels.

Type ii diabetes (T2D) patients in the UK got a new treatment option to control their blood sugar levels with the availability of FDA approved qtern drug from AstraZeneca. It is a fixed combination drug of 5 mg DPP-4 inhibitor (saxagliptin) and 10 mg SGLT2 inhibitor (dapagliflozin), to be used once in a day. The drug was approved by the European Union during July 2016 intended to improve glycemic control in type 2 diabetes patients when

  • The patient is already under the treatment of free combination of saxagliptin and dapagliflozin
  • Glycemic control was not achieved with the components of qtern


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Medical Cost Savings With Triglyceride And Statin Reducing Treatments

Triglyceride fat lipid LDL reducing statin treatment in dyslipidemia diabetes patients to save cost.

The blood condition in an individual with high levels of triglycerides, fat phospholipids and LDL cholesterol is known as dyslipidemia. Dyslipidemia blood condition is associated with the huge costs (price) to manage complications due to type 2 diabetes (T2D) condition. On the average, an American individual is spending $13,700 to take care of diabetes condition, according to the ADA. Researchers from Kaiser Permanente, based in California, United States says medical costs can be reduced with triglyceride lowering therapy in type ii diabetes (T2D) patients. Researchers conducted observational studies among 184,000 type 2 diabetes patients. Researchers compared triglyceride levels and medical costs before and after treatment intended to lower cholesterol and triglyceride levels. Study results show

  • Diabetes patients can get economic benefits with all types of lipid-lowering treatments.
  • More than average savings in medical costs when patients receive both statin and triglyceride (TG) combination therapy when compared with a diabetic individual undergoing either triglyceride (TG) or statin therapy.
  • Medical cost savings are marginally more with triglyceride (TG) monotherapy compared with statin monotherapy.
  • A statin and triglyceride (TG) combination therapy intended to reduce triglycerides by more than 30 percent got the maximum economic benefit.
  • A diabetes individual can save maximum economic benefit with a statin monotherapy with the reduction of triglycerides by more than 30 percent but to lesser amount compared with combination therapy.

But researchers unable to say the economic saving is due to the treatments or due to a reduction in triglyceride levels. The study findings were published in the American Journal of Cardiology.



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