Diabetes, Heart and Cardiovascular Diseases News Chronicle.  Diabetes, Cardiovascular and Heart Diseases
 Article 130
    Published on February 11, 2017


Risk With Enteroviruses In Children

Type 1 Diabetes Prediction and Prevention Study done by Finish researchers from the University of Tampere shows higher events of enterovirus infection condition in children before the onset of the autoimmune process leads to type 1 diabetes (T1D). Researchers analyzed enteroviruses viruses in stools to find out the association with islet autoimmunity in type 1 diabetes (T1D) patients. Previous studies linked increased enterovirus infections events to multiple diseases. They also linked the presence of these viruses in the pancreas and blood in individuals with type 1 diabetes (T1D).



Enterovirus infections may cause mild symptoms such as a headache, sore throat, fever and loss of appetite. Higher infected individuals may have following symptoms

  • Low levels of oxygen in the blood (hypoxia)
  • Common cold
  • Paralysis
  • Aseptic meningitis (inflammation in the brain and spinal membranes)
  • HFMD - Hand, foot and mouth disease
  • Conjunctivitis (infective in inner eyelids and outer membrane)
  • Encephalitis (brain inflammation due to infection)
  • Myopericarditis
  • Herpangina (a type of viral illness in children)
  • Pleurodynia (severe pain in the rib muscles)

Enterovirus infections with HFMD Encephalitis Herpangina in children leads to type 1 diabetes T1D.

Twelve months before the first signs of damage to the beta cell, researchers found higher levels of enterovirus infection, viruses in children and the presence of islet autoantibodies. Researchers say further investigations required to find out the mechanism behind this phenomena and to develop a vaccine against these viruses to understand the development of type 1 diabetes (T1D). The study findings were published in the journal Diabetologia.



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Stimulating Bone Stem Cells May Improve Bone Repair

The diabetic patient doesn't recover well from bone fractures and bone healing is one of the many complications faced by diabetes patients. A study done by researchers from the Stanford University School of Medicine, Palo Alto discovered a protein that stimulates bone stem cells to heal the fracture in a better way in experiments with diabetic mice. The researchers say their findings will lead to better treatment for bone repair in people with diabetes.




Stimulating bone stem cells may improve bone repair, healing from a bone fracture in a diabetic patient.

Researchers observed a reduction in the bone stem cell activity in mice during the development phase of diabetes. They also observed same phenomena in bone samples of a diabetic patient. The researchers discovered a protein which can stimulate bone stem cells in subsequent experiments. Researchers observed improved healing when they applied protein on bone fracture. Senior author of the study is Prof Michael T Longaker and the study findings were published in the journal Science Translational Medicine.



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Risk With Depression For Cardiovascular Diseases

More than 350 million people were affected by depression and 15 percent of cardiovascular deaths are due to depression. A study done by researchers from Helmholtz Zentrum Mnchen shows depression is a risk factor for cardiovascular diseases (CVD) in men and the risk factor is as great as for risk with obesity, high body mass index (BMI) and high cholesterol levels.




Blood pressure obesity BMI cholesterol depression are risk factors for cardiovascular diseases CVD.

Researchers analyzed data from 3,428 male patients, aged between 45-74. They completed observational studies for over 10 years. They analyzed the impact of depression over four major risk factors (1) smoking (2) obesity (3) hypertension and (4) high cholesterol levels and concluded above-mentioned finding. They also found that greater risk is associated with high blood pressure and smoking. Group leader of the study is Dr. Karl-Heinz Ladwig, Helmholtz Zentrum Mnchen (also a professor of psychosomatic medicine at DZHK) and the study findings were published in the Atherosclerosis.



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