Diabetes, Heart and Cardiovascular Diseases News Chronicle.  Diabetes, Cardiovascular and Heart Diseases
 Article 124
    Published on February 1, 2017


Study On Hormonal Contraception

Hormonal birth control medications such as transdermal patches, oral contraceptives and vaginal rings contain estrogen. Estrogen increases the risk of blood clotting, stroke and heart attack in women, even though they have no health problems. Risk increases by two to four times if the user is a diabetic patient. So doctors are unwilling to prescribe hormonal birth control medications.

Researchers from University of California Davis Health System conducted a study to find out health outcomes with hormonal contraception in patients with diabetes. Researchers used Clinformatics data, which contains 15 million reproductive-aged women individuals with type 1 and type 2 diabetes and analyzed cardiovascular events risk with hormonal birth control medications. Study results show no stroke or heart attack incidents in diabetic women using hormonal birth control. Analytical results data shows

  • Instances of cardiovascular events occurring each year were just 6.3 events per 1000 women
  • Usage of birth control measures such as IUDs and subdermal implants were least likely to be associated with increased risk of blood clotting, stroke and heart attack
  • Usage of birth control measures such as estrogen patches and injections with progestin showed a slightly higher risk of blood clotting, stroke and heart attack

Results also show 72 percent of diabetic women did not receive any kind of medication to control pregnancy. Researchers suggested physicians prescribe hormonal contraception to women with diabetes. Lead author of the study is Associate Prof Sarah O'Brien, Nationwide Children's Hospital and the study findings were published in the Diabetes Care.



       
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Metformin Prevents Cancer Growth

A study done by researchers from Massachusetts General Hospital (MGH) shows metformin (diabetes drug) can prevent or reduce the speed of growth of some types of cancer cells. Researchers studied effects of metformin drug on cancers such as prostate, pancreas and breast.

The nucleus of a cell determines structure and function of the body cell. The nucleus of a cell contains generic molecules - DNA. Researchers say metformin reduces traffic, that is "IN" and "OUT" movement of molecules from the nucleus. Metformin drug blocks cancer growth with the reduced molecules traffic causing an increase in lifespan. Senior author of the study is Dr. Alexander Soukas MD, PhD, MGH Center for Human Genetic Research and the study findings were published in the Cell.



       
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Babies Born To Diabetic Mother Often Bigger

A study done by researchers from European Society of Cardiology shows the size of the infant of the pregnant women with diabetes increases as blood circulates more into placenta in the fetuses instead of the brain. Medical experts say reduced blood circulation to the brain in utero (unborn child) affects the baby lifelong. Data suggests that babies of mothers with uncontrolled high sugar levels were bigger and the placenta is larger. Sometimes kidneys and pancreas were being affected. Lead Author of the study is Dr. Aparna Kulkarni.



       
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About Basaglar Insulin

Eli Lilly and Boehringer Ingelheim, manufacturers Basaglar glargine insulin announced that 100 units/ml strength Basaglar insulin can be used by both type 1 diabetes patients (children and adults) and type 2 diabetes patients (only adults). Medicine is available in 3ml pre-filled KwikPens, packed in a carton containing 5 units. Basaglar is a long-acting insulin approved by FDA in December 2015. This insulin is not to treat diabetic ketoacidosis condition. The patient should not to use during hypoglycemia condition or if the patient is allergic to glargine or any other component present in the insulin.



       
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